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KPV (10mg)

KPV is examined in inflammatory, epithelial barrier and immune modulation research models.
  • purity_percentage Icon 99% Purity
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KPV (50mg)
High-Purity Anti-Inflammatory and Immunomodulatory Peptide for Research Use

KPV (50mg) is a research-grade tripeptide (Lys-Pro-Val) derived from the C-terminal region of alpha-Melanocyte-Stimulating Hormone (α-MSH). It has been widely studied for its anti-inflammatory, gut-protective, and cellular repair properties in laboratory environments. KPV acts by interacting with melanocortin receptors (MC1R) and modulating key inflammatory signaling pathways.

Product Overview
KPV’s mechanism of action involves suppressing NF-κB activation and reducing the production of pro-inflammatory cytokines. In research settings, it has demonstrated relevance in studies of epithelial protection, oxidative stress regulation, and immune cell balance. Its natural origin, coupled with stability and versatility, makes KPV an essential model for immunological, gut, and skin research.

Key Research Attributes:

  • Anti-Inflammatory Action: Investigated for its ability to downregulate TNF-α, IL-6, and NF-κB activity in vitro.
  • Gut and Epithelial Studies: Commonly used in intestinal permeability and mucosal protection models.
  • Immune Regulation: Explored for its effects on macrophage polarization and innate immune signaling.
  • Skin and Tissue Repair: Studied in keratinocyte and dermal models to evaluate cellular protection and wound repair potential.
  • High Purity & Stability: Lyophilized and validated at >99% purity for reproducibility across biochemical and cellular studies.


Applications in Scientific Research

  • Inflammatory response and immune regulation studies
  • Gut and intestinal barrier research
  • Skin healing and epithelial cell function assays
  • Oxidative stress and cytokine modulation models
  • Melanocortin receptor pathway exploration

Format and Storage
Form: Lyophilized powder
Purity: >99%
Molecular Formula: C17H32N4O4
Molecular Weight: 356.47 g/mol
Storage: Store at -20°C for optimal stability
Reconstitution: Use bacteriostatic water for solution preparation

Disclaimer: KPV (50mg) is intended for laboratory research use only. It is not for human or veterinary use. All studies must adhere to institutional and regulatory guidelines.



Chemical Makeup

Sequence: Lys-Pro-Val

Synonyms: KPV Tripeptide, α-MSH (11–13), Anti-Inflammatory Peptide

 

Provided strictly for laboratory and research purposes. Please review our Terms and Conditions before placing an order.

Purity Percentage 99% Purity
Volume 50MG
Bought This Week 10
New Yes
Sale Yes

KPV (50mg): Research Overview, Anti Inflammatory Mechanisms, and Immunomodulatory Activity

KPV (Lys Pro Val) is a tripeptide fragment derived from the C terminal region of α Melanocyte Stimulating Hormone (α MSH). It has been widely studied as a model for anti inflammatory action, epithelial protection, and immune modulation. Research demonstrates its potential relevance in gut barrier integrity, cytokine signalling, oxidative stress response, and cutaneous repair.

  • •
    KPV and α MSH Anti Inflammatory Pathways
    Reviews KPV’s influence on NF κB activity, pro inflammatory signalling suppression, and melanocortin receptor interactions.
    Read more
  • •
    Intestinal Protection and Gut Barrier Studies
    Summarises experimental findings on epithelial reinforcement, colitis model recovery, and permeability regulation.
    Read more
  • •
    Cytokine Modulation and Inflammatory Signalling
    Discusses evidence of reduced TNF α, IL 1β, IL 6, and other inflammatory mediators following KPV exposure.
    Read more
  • •
    KPV in Skin Repair and Wound Closure
    Examines keratinocyte activation, reduced inflammation, accelerated closure, and dermal restoration in tissue models.
    Read more
  • •
    Macrophage Polarisation Research
    Reviews KPV’s potential ability to shift macrophage activity from inflammatory (M1) patterns toward regulatory (M2) states.
    Read more
  • •
    Epithelial Models and Antioxidant Mechanisms
    Provides insights into oxidative stress buffering, epithelial transport signalling, and immune co culture interactions.
    Read more

Disclaimer: KPV (50mg) is supplied strictly for laboratory research use only. It is not designed for human or veterinary application. All experiments must follow institutional and regulatory guidelines.

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Headspace oxygen displacement prevents oxidative degradation. Maintains compound integrity from manufacture to laboratory.

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Frequently asked questions

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Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.
Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

Why choose Peptide Centre? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

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Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

Can you give me dosage guidelines? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

What is included with each order? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

How can I verify the quality of your products? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

How can I verify the quality of your products? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

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