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Mots C (10mg)

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Research Benefits:

  • Mitochondrial Function Research: MOTS-c is extensively studied for its role in regulating mitochondrial metabolism and enhancing cellular energy output via activation of the AMPK pathway.
  • Metabolic Health Studies: Used in research models investigating insulin sensitivity, glucose utilization, and lipid oxidation in the context of metabolic syndrome and age-related decline.
  • Exercise Endurance Research: Explored for its potential to boost exercise capacity, stamina, and skeletal muscle efficiency in high-performance and fatigue-based studies.
  • Anti-Aging Applications: Valued in aging research due to its effects on mitochondrial protection, longevity signaling, and cellular resilience against metabolic stressors.
  • High-Grade Purity: MOTS-c is produced with >99% purity in lyophilized form, ensuring consistency and reproducibility in metabolic and bioenergetic research studies.

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MOTS-c (10mg)
Mitochondrial-Derived Peptide for Metabolic and Cellular Stress Research

MOTS-c (10mg) is a synthetic mitochondrial-derived peptide (MDP) encoded by the 12S rRNA region of mitochondrial DNA. It plays a central role in metabolic regulation, cellular homeostasis, and stress response signaling. This peptide has garnered significant interest in research focused on mitochondrial activity, insulin sensitivity, and age-related metabolic dysfunctions.

Product Overview
Each vial contains 10mg of MOTS-c in lyophilized form, synthesized to >99% purity. It is ideal for experimental studies investigating AMPK pathway activation, oxidative stress modulation, and insulin-mimetic mechanisms. Its unique mitochondrial origin distinguishes it from traditional peptides and supports its investigation in metabolic disease models.

Key Research Attributes:

  • Mitochondrial Regulation: MOTS-c is encoded within the mitochondrial genome and regulates cellular metabolism by activating AMPK and related energy pathways.
  • Insulin Sensitivity Support: Studied for its role in enhancing glucose uptake and mimicking insulin-like effects in cellular models.
  • Stress Response Signaling: Research suggests MOTS-c may protect cells under metabolic or oxidative stress, including hypoxia and aging environments.
  • Exceptional Purity: Formulated for precise and repeatable results in controlled laboratory settings.


Applications in Scientific Research

  • Mitochondrial function and peptide encoding studies
  • Metabolic syndrome and insulin resistance models
  • AMPK pathway and energy metabolism regulation
  • Oxidative stress and anti-aging cellular mechanisms
  • Neuroprotective and cytoprotective stress response investigations

Format and Storage
Form: Lyophilized powder
Purity: >99%
Storage: Store at -20°C in a sealed, moisture-free environment
Reconstitution: Use sterile bacteriostatic water in a sterile setting

Disclaimer: MOTS-c (10mg) is intended solely for in vitro and laboratory-based research. It is not for human or veterinary use. All handling must follow institutional and legal research guidelines.



Chemical Makeup

Molecular Formula

  • MOTS-c: C136H217N43O27

Molecular Weight

  • MOTS-c: 2188.5 g/mol

Sequence

  • MOTS-c: MRWQEMGYIFYPRKLR

Other Known Titles

  • MOTS-c: Mitochondrial Open Reading Frame of the 12S rRNA Type-c
 

MOTS-c (10mg) is supplied exclusively for scientific research use. Acceptance of our Terms and Conditions is required prior to ordering.

Research

MOTS-c Peptide: Research Insights and Applications

  • Metabolic Regulation through MOTS-c
    This review explores MOTS-c's role in activating AMPK and regulating glucose and lipid metabolism, supporting mitochondrial function and metabolic balance. Read more
  • Anti-Obesity Potential of MOTS-c in Animal Models
    Study shows that MOTS-c administration improves insulin sensitivity and reduces weight gain in high-fat diet mice. Read more
  • MOTS-c Enhances Exercise Capacity and Endurance
    Research demonstrates increased exercise performance in mice treated with MOTS-c, potentially via mitochondrial biogenesis. Read more
  • Longevity and Aging-Related Effects of MOTS-c
    MOTS-c has been investigated for its anti-aging potential, showing evidence of cellular protection and enhanced lifespan in preclinical studies. Read more
  • Neuroprotective Functions of MOTS-c Peptide
    Preclinical findings suggest MOTS-c can reduce neuroinflammation and support brain mitochondrial function. Read more
  • Immune Modulation and Inflammation Control
    MOTS-c's regulatory effects on immune responses and cytokine expression have been observed in autoimmune and inflammatory research models. Read more
  • Potential Application in Type 2 Diabetes Models
    Studies indicate MOTS-c can improve glucose tolerance and support insulin signaling pathways. Read more
  • MOTS-c and Cardiovascular Health
    Research suggests a protective effect on vascular integrity and heart function under metabolic stress conditions. Read more
  • Mechanistic Studies on MOTS-c and Cellular Energy Balance
    Detailed molecular pathways involved in MOTS-c’s action on cellular bioenergetics are outlined in this research article. Read more

MOTS-c Peptide: Research Insights and Applications

  • Metabolic Regulation through MOTS-c
    This review explores MOTS-c's role in activating AMPK and regulating glucose and lipid metabolism, supporting mitochondrial function and metabolic balance. Read more
  • Anti-Obesity Potential of MOTS-c in Animal Models
    Study shows that MOTS-c administration improves insulin sensitivity and reduces weight gain in high-fat diet mice. Read more
  • MOTS-c Enhances Exercise Capacity and Endurance
    Research demonstrates increased exercise performance in mice treated with MOTS-c, potentially via mitochondrial biogenesis. Read more
  • Longevity and Aging-Related Effects of MOTS-c
    MOTS-c has been investigated for its anti-aging potential, showing evidence of cellular protection and enhanced lifespan in preclinical studies. Read more
  • Neuroprotective Functions of MOTS-c Peptide
    Preclinical findings suggest MOTS-c can reduce neuroinflammation and support brain mitochondrial function. Read more
  • Immune Modulation and Inflammation Control
    MOTS-c's regulatory effects on immune responses and cytokine expression have been observed in autoimmune and inflammatory research models. Read more
  • Potential Application in Type 2 Diabetes Models
    Studies indicate MOTS-c can improve glucose tolerance and support insulin signaling pathways. Read more
  • MOTS-c and Cardiovascular Health
    Research suggests a protective effect on vascular integrity and heart function under metabolic stress conditions. Read more
  • Mechanistic Studies on MOTS-c and Cellular Energy Balance
    Detailed molecular pathways involved in MOTS-c’s action on cellular bioenergetics are outlined in this research article. Read more
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