Your cart is ready — click here to view your products.

Free shipping on orders over $200 USD • COA included with every order • Research use only

Best Seller

Tirz (GLP-1 / GIP)

Tirz is examined in glucose control, weight management and cardiometabolic research models.
  • purity_percentage Icon 99% Purity
$129
$189
Bundle & Save:
bootstrap/verify Same day dispatch
bootstrap/verify COA included
bootstrap/verify 72 hour delivery (AU)
bootstrap/verify Secure checkout
bootstrap/FreeShipping

Free Shipping

Free Shipping Over $400

bootstrap/ConfirmedPurity

≥99.1%

HPLC Confirmed Purity

bootstrap/SameDayDispatch

Same Day Dispatch

Order Before 2PM AEST

bootstrap/Verification

3rd Party

COA Verification

bootstrap/FlexiblePayment

Flexible Payment

Shop Now pay later

 

Tirz (GLP-1)
Dual Incretin Peptide for Metabolic, Endocrine, and Obesity Research

Tirz is a synthetic dual agonist of the GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. This novel peptide is of great interest in metabolic and endocrine research, particularly in models involving glucose regulation, energy balance, and weight management pathways.

Product Overview
Supplied in lyophilized format, Tirz is available for in vitro and preclinical exploration in models evaluating insulin sensitivity, adipocyte function, and incretin hormone signaling.

Key Research Attributes:

  • GLP-1 and GIP Dual Activity: Mimics endogenous incretins to enhance glucose-stimulated insulin secretion and satiety signaling.
  • Insulin Sensitivity: Explored in studies assessing improved glucose uptake and pancreatic beta-cell preservation.
  • Body Weight Modulation: Utilized in obesity-related research targeting reduced energy intake and enhanced metabolic expenditure.
  • Chronic Disease Models: Investigated in laboratory models of metabolic syndrome, type 2 diabetes, and lipid metabolism disorders.


Applications in Scientific Research

  • Incretin pathway and peptide hormone signaling studies
  • Glucose homeostasis and insulin secretion models
  • Obesity and energy regulation research
  • Liver lipid metabolism and hepatic steatosis studies
  • Endocrinology-focused preclinical experiments

Format and Storage
Form: Lyophilized powder
Purity: >99%
Storage: Store at -20°C in a dry, dark location
Reconstitution: Reconstitute with sterile bacteriostatic water under aseptic conditions

Disclaimer: Tirz (GLP-1) is provided exclusively for laboratory-based, in vitro scientific research. It is not intended for human or veterinary use. All handling must comply with institutional and legal safety requirements.



Chemical Makeup

Molecular Formula

  • Tirz: C225H348N48O68

Molecular Weight

  • Tirz: 4813.5 g/mol

Other Known Titles

  • Tirz: LY3298176, Dual GIP/GLP-1 Receptor Agonist
 

Tirz (GLP-1) is intended for qualified scientific research use only. All purchases are subject to our Terms and Conditions.

Purity Percentage 99% Purity
Volume 10MG
Bought This Week 435
New No
Sale Yes

Tirz Research: Effects, Benefits, and Side Effects

Tirz is a dual-pathway metabolic peptide under investigation for its effects on weight management, glycaemic control, and cardiometabolic risk reduction. Clinical and preclinical research has explored its role in obesity, type 2 diabetes, kidney function, and potential neuroprotective outcomes. Long-term safety data are still evolving, and ongoing studies continue to refine understanding of its benefits, limitations, and side-effect profile. The sources below summarise proposed mechanisms, benefits, and reported adverse effects.

  • •
    Tirz: A Comprehensive Review of Clinical Efficacy, Safety, and Future Implications
    Provides an in-depth overview of Tirz’s mechanism of action, weight management benefits, glycaemic support, and emerging safety insights.
  • •
    Tirz Slows Progression of Kidney Disease in Type 2 Diabetes
    Summarises findings showing Tirz may slow the progression of chronic kidney disease in metabolic research models.
  • •
    Adverse Effects with Tirz: Meta-Analysis Protocol
    BMJ Open protocol discussing a systematic review of Tirz-associated side effects and adverse event trends.
    Read more
  • •
    Metabolic Benefits of Tirz: A Narrative Review
    Explores cardiovascular, metabolic, and neuroprotective benefits observed in emerging research.
    Read more
  • •
    Tirz Shown to Improve Heart Health & Reduce Weight
    Reviews dual benefits involving significant reductions in body fat and improvements in cardiovascular markers.
  • •
    Three-Year Weight Loss Results from Tirz
    Long-term clinical data highlighting sustained reductions in body weight over multi-year periods.
  • •
    Neuroprotective Effects of Tirz
    Examines potential cognitive and neurological benefits observed in preclinical and translational models.
    Read more
  • •
    Tirz Overview: How It Works, Side Effects, and Cost
    A full guide covering dosing patterns, administration, mechanism of action, and safety considerations.
  • •
    Tirz Lowers Risk of Death in Type 2 Diabetes
    Investigates clinical evidence showing reduced all-cause mortality rates among diabetic subjects receiving Tirz.
bootstrap/verify The Difference

Not all peptide suppliers are equal

Research integrity depends on source transparency. See how Peptide Centre compares.

bca watter

Why we are different

White logo White logo

Purity Without Compromise.

others

Other Brands

Unknown Quality

Other

bootstrap/Verification
Quality & Purity
bootstrap/check-circle
99% purity guaranteed
bootstrap/x-circle
Unknown purity, inconsistent testing
bootstrap/tested
THIRD PARTY TESTED
bootstrap/check-circle
Regularly updated COAs for every batch
bootstrap/x-circle
Rare or no testing available
bootstrap/reputation
REPUTATION
bootstrap/check-circle
One of the most reputable global peptide brands
bootstrap/x-circle
Little to no customer proof. AI generated product
bootstrap/welcomekit
WELCOME KIT
bootstrap/check-circle
Products come in a reusable storage box, with BAC water and relevant COAs
bootstrap/x-circle
Unsecure, non-discreet packaging causing product potency issues
bootstrap/productrange
PRODUCT RANGE
bootstrap/check-circle
We stock over 50 peptides, blends and bundles for your research
bootstrap/x-circle
Limited peptide range with no supporting products
bootstrap/shipping
SHIPPING
bootstrap/check-circle
Same day dispatch and 2-4 day deliver within the US, Australia and the UK
bootstrap/x-circle
Long delivery times, unclear tracking and limited shipping coverage
bootstrap/payments
PAYMENT SECURITY
bootstrap/check-circle
Multiple payment methods such as credit card and bank transfer
bootstrap/x-circle
Limited payment methods, often bank transfers only
bootstrap/support
CUSTOMER SUPPORT
bootstrap/check-circle
Real people, real support, fast and informed. 7 days per week
bootstrap/x-circle
Generic responses or no support at all
bootstrap/verify Why Peptide Centre

Pure science, delivered

bootstrap/Purity

99%+ HPLC Purity

Every batch independently verified via high-performance liquid chromatography.Full trace included with shipment.

bootstrap/Analysis

Full Certificate of Analysis

Mass spectrometry, HPLC trace, sequence confirmation, and batch number. Third-party verifiable on request.

bootstrap/Complimentary

Complimentary Welcome Kit

Every order includes a premium welcome kit with bacteriostatic water, with your peptides remaining in lyophilised form to maintain optimal quality until reconstitution.

bootstrap/verify

Argon-Flushed Vials

Headspace oxygen displacement prevents oxidative degradation. Maintains compound integrity from manufacture to laboratory.

bootstrap/verify Research Support

Frequently asked questions

What are peptides? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.
Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

Why choose Peptide Centre? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

How does shipping and delivery work? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

Can you give me dosage guidelines? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

What is included with each order? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

How can I verify the quality of your products? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

How can I verify the quality of your products? circledown

Retatrutide is characterised in preclinical research for its simultaneous affinity for three distinct receptor classes. This tripartite agonist profile differentiates it from earlier dual-agonist analogues and makes it a subject of significant interest in receptor binding and pharmacodynamic research models.

  • 3 Vials Save 32%1 Free- $387
  • 6 Vials Save 32%2 Free- $774
  • 9 Vials Save 32%3 Free- $1,161